Longevity News & Review

By Robert Goldman
For The Bali Times

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 20,000 physician and scientist members from 90 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, A4M president, and Dr. Robert Goldman, A4M chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their commentary

Antioxidant Flavonols Slash Risk of Colorectal Cancer
Flavonols are a type of antioxidant compound found in higher concentrations in teas, onions, beans and apples. In that two recent case-control studies have suggested that some flavonoid subgroups may play a role in preventing colorectal cancer, Gerd Bobe, from the National Cancer Institute in Maryland, and colleagues utilized the newly constructed US Department of Agriculture flavonoid database to examine the association between flavonoid consumption and the onset of pre-cancerous colorectal polyps. Studying data from more than 2,000 men and women who consumed either a diet low in fat, high in fiber, and rich in fruits and vegetables, or a normal diet, the team found that those study participants who consumed more flavonols reduced their risk of colorectal tumors by 76 percent. Conclude the researchers: “Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence.”

Dr. Klatz observes: As the third most common cancer globally, almost one million new cases of colorectal cancer are diagnosed worldwide. In that a diet high in fat, refined carbohydrates and animal protein increase colorectal cancer risk, this study is important in that it acknowledges a role for flavonols to reduce one’s risk.

Rheumatoid Arthritis Doubles Cardiovascular Disease Risk
Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in the joints, most commonly the wrist and fingers. Revealing findings of two studies at the 2008 Congress of the European League Against Rheumatism, Dr. Mike Peters reported that patients who suffer from RA are two-times more likely to develop cardiovascular disease (CVD), compared to those who do not have the disease. Additionally, Dr. Peters and co-researchers found similarities between patients with type-2 diabetes and RA regarding the risk of CVD. They determined that the odds of CVD were 2.3 for those with type-2 diabetes and 2.0 for those with RA.

Remarks Dr. Goldman: In the United States alone, an estimated 1.3 million adults aged 18 and older had RA in 2005, and the disease affects twice as many women as men. These two study findings suggest that rheumatoid arthritis should not be overlooked as a key risk factor for cardiovascular disease. People suffering from RA should be encouraged to follow a healthy diet and lifestyle and to be alert to the early signs and symptoms of CVD.

Coffee Reduces Death Risk Due to Heart Disease
A large-scale prospective study reports that men and women who enjoy a few cups of coffee each day have a lower risk of dying from heart disease than those who don’t drink the beverage. Esther Lopez-Garcia, from the Harvard School of Public Health, and colleagues studied 20 years’ of data from 41,736 men who participated in the Health Professionals Follow-up Study, and 86,214 women involved in the Nurses’ Health Study. The researchers found that in general, regular coffee consumption was linked to a slightly lower risk of death from any cause, and from cardiovascular disease in paerticular. Among women, those who drank at least two to three cups per day were one-quarter to one-third less likely to die of heart problems or stroke than women who did not drink coffee. For men, a protective effect was seen when drinking four to five cups daily. The researchers point to: “The possibility of a modest benefit of coffee consumption on all-cause and CVD mortality.”

Comments Dr. Klatz: Coffee has, in previous studies, been shown to have a mitigating effect on certain diseases, including type-2 diabetes and Parkinson’s Disease. Some researchers have also found that coffee reduces inflammation in blood vessels and supports the normal function of the blood vessel lining. It is possible that the constituents in coffee, such as magnesium and antioxidant compounds, are responsible for the beverage’s beneficial effects.

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