Longevity News & Review

By Robert Goldman
For The Bali Times

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 20,000 physician and scientist members from 90 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, A4M president, and Dr. Robert Goldman, A4M chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their commentary

Specific Cancer-Protective Vegetables Identified
A number of studies have established that an abundant consumption of fruits and vegetables reduces the risk of developing several types of cancers. Dominique Boivin, from Saint Justine Hospital (Quebec, Canada), and colleagues embarked on a study to identify specific fruits and vegetables that exert the most potent cancer protective properties. The team analyzed the effects of extracts isolated from 34 vegetables on eight different cancer cell lines, namely stomach, lung, breast, kidney, skin, pancreas, prostate and brain. Cruciferous vegetables (including broccoli, kale, and brussels sprouts) and Allium vegetables (such as garlic) exerted the most significant cancer inhibition. In contrast, the researchers found that vegetables such as potato, carrot, tomato and lettuce were ineffective at providing cancer protection. The study team suggests that the chemopreventive effects of cruciferous and allium vegetables are likely related to the formation of organosulfur compounds upon their ingestion.

Dr Klatz remarks: ‘Popular’ vegetables such as potatoes, carrots, tomatoes and lettuce, account for nearly 60 percent of the total per capita vegetable intake in the US adult population. This study correlates a potential preventive role for cancer of ‘unpopular’ vegetables, such as those in the cruciferous and allium families. These findings underscore the importance of daily consumption of a variety of vegetables, to achieve the optimal intake for disease protection and prevention.

Red Wine Lowers Risk of Lung Cancer in Men
In men in the United States, lung cancer is the second leading cause of death by all cancer types. Chun Chao, from Kaiser Permanente Southern California, and colleagues analyzed data collected from 78,168 men (ages 45 to 69) enrolled in the California Men’s Health Study, assessing lifestyle factors, dietary intakes, alcohol consumption and tobacco smoking. On average, there was a 2-percent lower risk of lung cancer associated with each glass of red wine consumed per month. Among long-time smokers, the risk reduction rose to 4 percent. The team found no clear association between the consumption of other types of alcohol and the risk of lung cancer.

Dr. Goldman observes: This study suggests the presence of specific compounds in red wine that are protective against lung cancer. Analyses of red wine have revealed that it is high in flavonoids, a group of potent antioxidants, and resveratrol, a compound which has consistently been linked to health benefits.

Vitamin D Deficiency Linked to Parkinson’s Disease
Parkinson’s Disease (PD) is a progressive, degenerative neurological disease characterized by tremor, rigidity, stooped posture and other symptoms. Manan Evatt, from Emory University School of Medicine, and colleagues have completed a study of 300 adults and found that 55 percent of people with PD are deficient in Vitamin D, as compared to 36 percent of age-matched healthy control subjects. Previous, separate studies have shown that the part of the brain affected by PD contains high levels of the Vitamin D receptor, suggesting it may be important for normal function of these cells. Conclude the researchers: “… higher prevalence of [vitamin D deficiency] in PD … support[s] a possible role of vitamin D insufficiency in PD. Further studies are needed to determine the factors contributing to these differences and elucidate the potential role of vitamin D in pathogenesis and clinical course of PD.”

Comments Dr. Klatz: The number of individuals with Parkinson’s disease in 15 of the world’s largest nations will double over the next 25 years. In the five nations comprising Western Europe (France, Spain, Germany, the United Kingdom and Italy) and the 10 most populous nations worldwide (China, India, Indonesia, the United States, Brazil, Pakistan, Bangladesh, Nigeria, Japan and Russia), experts have projected that the number of individuals with Parkinson’s disease in these 15 countries will grow from 4.1 to 8.7 million by the year 2030. This study points to the necessity for further research to elucidate the exact causal mechanism for a potential therapeutic role of Vitamin D to treat or prevent Parkinson’s.

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