Longevity News & Review

By Dr. Robert Goldman
For The Bali Times

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their commentary.

Bad Marriages Take Toll on Women’s Health
Negative affect and social behavior may be soon considered as risk factors for coronary heart disease in women. Nancy Henry, from the University of Utah, and colleagues studied 276 healthy older couples (average age 54; average duration of 27.5 years in married relationship), evaluating each for positive and negative aspects of their relationships. The team found that while both men and women in strained marriages showed signs of anger or depression, women in such relationships were more likely to develop high blood pressure, high cholesterol, high blood sugar and other markers of metabolic syndrome, a condition that increases the risk of heart disease, stroke, and diabetes. Men were as likely to become depressed with marital strain, but the link between negativity, depression, and metabolic syndrome only applied to women.

Dr Klatz remarks: This study presents interesting findings, and may suggest the potential for depression to be a possible mechanism thorough which emotional strain influences metabolic syndrome. Truly, then, a strained marriage may very well be very bad for your health.

In Older Women, Metabolic Syndrome Raises Risk of Cognitive Impairment

Metabolic Syndrome is a group of health risk factors that are associated with cardiovascular disease and diabetes. Factors include enlarged waist circumference, high blood pressure, elevated triglycerides, low HDL (“good”) cholesterol and high fasting glucose levels. Kristine Yaffe, from the University of California-San Francisco, and colleagues studied 3,054 elderly men and women enrolled in The Health, Aging and Body Composition study, measuring body fat levels and correlating that data to mental status examination test scores. Women with Metabolic Syndrome were 66-percent more likely to develop cognitive impairment over the study’s four-year period (as compared to women who did not have metabolic syndrome). The team also found that among all women, there was a 23-percent increase in the risk of developing cognitive impairment for each additional component of Metabolic Syndrome (ie obesity, high cholesterol, high blood pressure, low LDL levels, and high blood sugar).

Dr. Goldman observes: This study is important in that it elucidates yet another negative consequence of Metabolic Syndrome. Metabolic Syndrome may contribute to cognitive impairment by promoting cerebrovascular disease, hindering the clearance of brain plaques associated with Alzheimer’s Disease, or elevating inflammation in the brain.

In Women, Depression Linked to Fatal Cardiac Events
Depression is a risk factor for cardiac events and mortality among those with coronary heart disease, possibly a result of arrhythmia. William Whang, from Columbia University Medical School, and colleagues have found that women who have symptoms of depression may be at increased risk of fatal cardiac events. The team assessed 63.469 women participants of the Nurses’ Health Study. At the study’s start, none of the selected subjects had coronary heart disease. The researchers assessed for depressive symptoms over an 8-year period, finding that these were associated with coronary heart disease events, with the strongest correlation to fatal events. Further, clinically diagnosed depression was strongly associated with sudden cardiac death. The team speculates that the elevated mortality risk associated with depression may be due to an increased risk of fatal ventricular arrhythmias.

Comments Dr. Klatz: This is a large-scale prospective study suggesting that depression may have a major role in fatal cardiac events in women. While the causality remains unclear, the data do suggest that maintaining a positive mental state may not only be health promoting, but very well may be life-saving.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your FREE subscription to The Anti-Aging News Journal.

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