Longevity News & Review

By Dr. Robert Goldman
For The Bali Times

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their commentary.

High Blood Lead Levels Linked to Heart Deaths

Lead is a toxic metal, and numerous studies suggest strong evidence of adverse health effects from lead exposure. Naila Khalil, from the University of Pittsburgh, and colleagues studied 533 women aged 65 to 87 years old for roughly 12 years. The team found that the women with lead concentrations above 8 micrograms per deciliter of blood were 59 percent more likely to die of any cause, and three times more likely to die of heart disease (as compared to women with lower blood lead levels). Warn the researchers: “Despite declines in blood lead concentrations during the past 30 years, environmental lead exposure continues to be a public health concern.”

Dr Klatz remarks: While many factors may contribute to the development of heart disease, this study provides strong data suggesting that lead exposure may be a major unrecognized contributor to the condition. This study also demonstrates the need for vigilance in reducing lead pollution, in order to correct and minimize the situation for future generations.

Weight Gain Early in Life Leads to Physical Disabilities in Older Adults
Carrying extra weight earlier in life increases the risk of developing problems with mobility in old age, even if the weight is eventually lost, report Denise Houston, from the Wake Forest University School of Medicine, and colleagues. The team studied 2,845 American adults, ages 70 to 79 years, enrolled in the Health, Aging and Body Composition Study, collecting and analyzing data on Body Mass Index (BMI) and mobility limitations during a seven-year follow-up period. Men and women who were overweight or obese at all three time points of the study had an increased risk of mobility limitation (as compared with those who were normal weight throughout). Further, the researchers found a significant graded response on risk of mobility limitation for the cumulative effect of obesity in men and overweight and/or obesity in women. Concludes the team: “Onset of overweight and obesity in earlier life contributes to an increased risk of mobility limitation in old age.”

Dr. Goldman observes: The aging population in the United States is growing, and the ranks of people in seniorhood are expected to double by the year 2030 to about 20 percent. It is important to stop and counter the trend towards declining rates of physical disability in older adults, because carrying extra weight can strain joints, hinder exercise and lead to chronic conditions, such as diabetes, arthritis and heart disease, and many of these directly lead to the development of mobility limitations. This study provides important data suggesting that that interventions to prevent overweight and obesity in young and middle-aged adults may indeed be useful in preventing or delaying the onset of mobility limitations later in life.

Having a Bigger Waistline Boosts Heart Failure Risk
In that obesity is associated with heart failure incidence, Emily B. Levitan, from Beth Israel Deaconess Medical Center, and colleagues examined the correlation between body mass index (BMI) and waist circumference with heart failure as a function of age. The team studied self-reported height, weight and waist circumference data on 36,873 women, ages 48 to 83, and 43.487 men, ages 45 to 79, collected over a five-year period. Every 10-cm increase in waist circumference raised the risk by 15 to 20 percent. In women, rising BMI, independent of waist circumference, did not predict the risk of heart failure hospitalization or mortality. Among men, however, both a greater waist circumference and greater BMI posed an increasing heart failure hazard.

Comments Dr. Klatz: With the worldwide incidences of both obesity and heart failure on the rise, this large-scale study provides valuable data demonstrating the hazards of a bigger waist circumference, increasing the risk of heart failure hospitalization and death in men and women. Further, in men a greater BMI increases heart failure risk independent of waist circumference. These data underscore the importance of maintaining a healthy BMI as well as lean waistline.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.

Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your FREE subscription to The Anti-Aging News Journal.

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