Longevity News & Review

By Dr Robert Goldman
For The Bali Times

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their commentary.

Where You Live May Affect Cancer Survival
Survival from breast and prostate cancer is influenced by racial disparities. Jaymie R. Meliker, from the State University of New York at Stony Brook, and colleagues have elucidated the role of societal/socioeconomic factors and innate/genetic factors that may explain these disparities. The team reviewed data from The Michigan Cancer Surveillance Program, comprised of data compiled from 1985 to 2002 that included 124,218 breast cancer cases and 120,615 prostate cancer cases with 5-year survival rates of 78 and 75 percent, respectively. The researchers noticed that as the geographic scale gets smaller, the population becomes more homogeneous in terms of income, access to medical care, and other factors that may influence cancer survival. They speculated that if racial disparities in cancer survival diminished when smaller geographic areas were analyzed, modifiable factors, rather than genetics, may be responsible for the disparity. The team found that whites had significantly higher survival rates of prostate and breast cancer compared with blacks when large geographic regions were analyzed. However, when smaller geographic areas were analyzed, such as legislative districts and neighbourhoods, disparities diminished or virtually disappeared. Conclude the researchers: “When racial disparities vanish in small geographic areas, it suggests that modifiable factors are responsible for apparent racial disparities observed at larger geographic scales … the current findings suggest that genetic factors are not likely to play a large role in disparities of survival from prostate and breast cancer.”

Dr Klatz remarks: This study suggests that cancer survival may be affected by variables other than innate or genetic factors. It presents intriguing data that external and modifiable forces, such as social and economic factors, may influence the prognosis for cancer patients.

Mediterranean Diet Associated with Lower Risk for Heart Disease
The Mediterranean diet is rich in cereals, fruits, legumes and whole grains, fish and olive oil. Numerous previous studies have shown those who follow the Mediterranean diet live longer, have less heart disease, and a reduced risk of cancers. Andrew Mente, from the Population Health Research Institute, and colleagues conducted a review of nearly 200 clinical studies of the Mediterranean diet pattern published in the last 50 years, finding it to be clearly associated with lowering the risk of heart disease. The team wrote that: “We identified strong evidence of a causal relationship for protective factors, including intake of vegetables, nuts and monounsaturated fatty acids and Mediterranean, prudent and high-quality dietary patterns, and harmful factors, including intake of trans-fatty acids and foods with a high glycemic index or load and a western dietary pattern. Among these dietary exposures, however, only a Mediterranean dietary pattern has been studied in randomized controlled trials and significantly associated with coronary heart disease.”

Dr. Goldman observes: Previously, research on the Mediterranean Diet has established its protective role in cardiovascular disease, cancer, certain chronic diseases, and premature death in the general population. This review of data from 200 clinical studies spanning a 50-year period clearly reaffirms a direct and protective relationship of the Mediterranean Diet pattern on coronary heart disease.

Omega-3 Linked to Lower Levels of Inflammation
Previous studies have shown that omega-3 fatty acids have anti-inflammatory properties and are associated with reduced cardiovascular disease risk. Manohar Garg from The University of Newcastle, Australia), and colleagues studied a group of 124 men and women living in the general community (average age 47.7 years), and studied their CRP level, a marker of low-grade sustained inflammation, as a function of circulating levels of omega-3 fatty acids. The team found that the omega-3 fatty acids concentration to be inversely correlated with CRP levels in healthy individuals. Observe the researchers: “Given that omega-3 fatty acids are cardioprotective, this inverse correlation with CRP, a surrogate marker of cardiovascular disease risk, could represent a possible mechanism by which omega-3 fatty acids are involved in cardiovascular disease risk reduction.”

Comments Dr. Klatz: This study’s findings support previous observations that omega-3 fatty acids may improve cardiovascular health in healthy individuals. This data suggests a future preventive role for omega-3 fatty acids in reducing the risk of cardiovascular disease.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your FREE subscription to The Anti-Aging News Journal.

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