April 23-29, 2010

By Dr Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Ronald Klatz, M.D., D.O., A4M President, and Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.

Aspirin Improves Breast Cancer Survival
In that animal and laboratory studies suggest that aspirin may inhibit breast cancer metastasis, Michelle D. Holmes, from Harvard Medical School, and colleagues studied whether aspirin use among women with breast cancer decreased their risk of death from breast cancer.  The team analyzed data collected from 4,164 female registered nurses in the Nurses’ Health Study who were diagnosed with stages I, II or III breast cancer between 1976 and 2002 and were observed until death or June 2006, whichever came first. Excluding aspirin use assessments in the first year after diagnosis because its use is discouraged during chemotherapy, the researchers found that among these women who survived for more than a year after diagnosis, those who used aspirin more were less likely to subsequently die from breast cancer, with an aspirin at least two days a week significantly reducing breast cancer death risk by 64 percent to 71 percent. The team concludes that: “Among women living at least one year after a breast cancer diagnosis, aspirin use was associated with a decreased risk of distant recurrence and breast cancer death.”

Dr. Klatz observes: Harvard University’s team makes a critical discovery that breast cancer survivors who take an aspirin at least two days a week reduce their risk of death due to breast cancer by up to 71 percent. It adds to data suggesting therapeutic benefits of daily low-dose aspirin consumption.

Migraine May Increase Cardiovascular Risks
In an effort to explore the relationship between migraine and cardiovascular disease, Marcelo E. Bigal, from Albert Einstein College of Medicine (New York), and colleagues studied 6,102 people with migraine and 5,243 people without migraine, surveying them for questions about headaches, treatment, general health and any diagnosed heart problems. The researchers found that people who had migraines were about twice as likely to have a heart attack compared to people without migraines, or 4.1 percent of people with migraine compared to 1.9 percent of those without migraine. The risk was nearly three times greater for people who experienced migraine with aura, or sensations such as seeing flashing lights that come before the migraine headache, compared to people without migraines. The team also found that people with migraine with aura were one and half times more likely to have diabetes and high cholesterol compared to people without migraine.

Remarks Dr. Goldman: In revealing that people who suffer from migraines may be at an increased risk of heart attack and other risk factors for heart disease, this research team identifies a very critical and significant correlation that may be rooted in circulatory dysfunction.

Oats Reduce Inflammation
Oats have been long proposed to have heart healthy benefits, and US Agriculture Research Services researchers have elucidated the mechanism for this association. Previously Mohsen Meydani, from Tufts University (Massachusetts), and colleagues have shown that phenolic antioxidants in oats obstruct the ability of blood cells to stick to artery walls. In new research, the team has found that another oat compound, avenanthramides, decrease the expression of pro-inflammatory cytokines. The study provides additional indications of the potential health benefit of oat consumption in the prevention of coronary heart disease beyond its known effect through lowering blood cholesterol.

Comments Dr. Klatz: Avenanthramides, compounds found in oats, decrease expression of inflammatory molecules to provide potential benefits for cardiovascular disease. This finding opens an important potential interventive role for the food in promoting heart health.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavours and to sign up for your free subscription to the Longevity Magazine™ e-Journal.

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