June 11-17, 2010
By Dr Robert Goldman
Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Ronald Klatz, M.D., D.O., A4M President, and Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.
Vitamin K May Slash Cancer Risk
Previous studies have elucidated benefits of vitamin K2, most notably in promoting bone and cardiovascular health. Jakob Linseisen, from the German Research Centre for Environmental Health, and colleagues studied 24,340 subjects, ages 35 to 64 years, enrolled in the EPIC-Heidelberg study. The participants were following for over 10 years, during which 1,755 cases of cancer were documented, with 458 of these as fatal. The team found that those study subjects with the highest average intakes of vitamin K2 were 14 percent less likely to develop cancer compared to people with the lowest average intakes. Furthermore, increased vitamin K2 intakes corresponded to a 28-percent reduction in cancer mortality.
Dr. Klatz observes: In finding that the consumption of foods rich in vitamin K2, found in meats and cheeses, may reduce the risk of various cancers, this German team has provided the latest evidence of an interventive role for a lesser-known nutrient in disease prevention.
Protein Linked to Dementia
C-reactive protein (CRP) is a marker of inflammation and vascular disease that has been associated with an increased risk of dementia. Heike Wersching, from University of Muenster in Germany, and colleagues studied 447 men and women, average age 63 years, without stroke or dementia. The participants underwent MRI brain scans and completed tests that measured verbal memory, word fluency and executive function, the process in the brain that allows for planning, decision making and selection of appropriate behaviour. The researchers found that higher levels of CRP corresponded to worse performance in executive function. Higher levels of the protein also affected the frontal lobe of the brain, where some motor functions take place. The team concludes that: “These data suggest that low-grade inflammation as assessed by high-sensitivity C-reactive protein is associated with cerebral microstructural disintegration that predominantly affects frontal pathways and corresponding executive function.”
Remarks Dr. Goldman: C-reactive protein, a marker of inflammation and vascular disease that has been associated with an increased risk of dementia, may exacerbate problems with executive thinking skills. This is an important discovery in that it may lead to new approaches to combat dementia and Alzheimer’s Disease by mitigating the inflammatory process.
Risks of Everyday Chemical Exposures
Throughout our lives we are exposed to a variety of chemicals, contained in food, water, medicines, the air we breathe, cosmetics and healthcare products, shoes, clothing and other consumer products. In the natural environment, living organisms are also exposed to a complex cocktail of chemical substances. The European Union Directorate-General for the Environment has commissioned a report to identify the extent of the health risks associated with such everyday chemical exposures. Observing that: “The number of chemical combinations that the Earth’s living organisms are exposed to is enormous,” the research team urges that: “We need guidelines on how to manage the chemical cocktail effect so that we can assess the risks to both humans and the environment.”
Comments Dr. Klatz: The European Union Directorate-General for the Environment has commissioned a very important report that identifies the health risks associated with everyday exposures to chemicals. It is an important acknowledgement of the potential dangers of hidden constituents that may be contained in food, water, medicines, the air we breathe and consumer products.
Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
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