Oct. 29-Nov. 04, 2010

By Dr Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 22,000 physician and scientist members from 105 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, and Dr Ronald Klatz, M.D., D.O., A4M President, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.

Workplace Enhances Post-Retirement Years
In many aspects, the workplace has displaced the neighbourhood and civic activities as the focal point of one’s social structure.  Rabina Cozijnsen, from VU University Amsterdam, and colleagues found that one’s workplace serves a primary role in prompting social interaction and developing  personal relationships. The team reports that men and women who retired just 10 years ago, at the beginning of the 21st century, were more likely to maintain (or even gain) work-related personal ties after retirement, compared to those who retired in the 1990s. Further, they observed that a majority of more recent retirees have at least one work-related tie in their personal network.  The researchers posit that: “Retirement has become less disruptive. Retirees seem more inclined to form intrinsically rewarding work-related relationships that continue to be important following retirement.”

Dr Klatz observes: Among workers who retire, maintaining work-related personal connections enhances social structure. This finding reinforces the importance of interpersonal relationships as we age.

Berries Boost Brain Health 
Blueberries and strawberries are high in antioxidant and anti-inflammatory compounds. Shibu M. Poulose, from the Tufts University Human Nutrition Research Center on Aging, and colleagues have found that polyphenol antioxidants present in berries help microglia, cells in the brain, to clean up toxic proteins linked to age-related memory loss and cognitive decline. Explaining that polyphenolics in berries appear to help maintain proper microglial functioning, the team concludes that: “The results strongly suggest that the benefits of both berries extend beyond the antioxidant and anti-inflammatory effects to cellular toxic clearance through induction of autophagy in brain.”

Remarks Dr Goldman: High in antioxidant and anti-inflammatory compounds, blueberries and strawberries scrub up toxic proteins. This finding may open new interventive nutritional approaches to thwart age-related memory loss and cognitive decline.
 
Pepper May Help Manage Weight  
Capsinoids, the non-pungent compounds found in sweet pepper, help to boost energy utilization, thus suggesting a role in weight management. Stuart M. Phillips, from McMaster University, and colleagues studied how capsinoid ingestion affects energy expenditure, including its role in exercise. The team recruited 12 healthy young men  (average age 24.3 years, average BMI 255.5 kg/m2), who were randomly assigned to receive a 10mg capsule of purified capsinoids or placebo (control group). The subjects then engaged in 90 minutes of moderately intense cycling. Finding that: “The ingestion of 10 mg of capsinoids increased adrenergic activity, energy expenditure and resulted in a shift in substrate utilization toward lipid at rest but had little effect during exercise or recovery,” the team submits that their data shows that: “The thermogenic and metabolic effects of capsinoids at rest and further promote its potential role as an adjunct weight loss aid, in addition to diet and exercise.”

Comments Dr Klatz: A Canadian team reveals that capsinoids, the non-pungent compounds found in sweet pepper, help to boost energy utilization, thereby suggesting a functional health role for this popular food.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at
www.worldhealth.net, to learn more about the A4M and its educational endeavours and to sign up for your free subscription to the Longevity Magazine™ e-Journal.

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