June 17-23, 2011

By Dr Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, and Dr Ronald Klatz, M.D., D.O., A4M President, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.

Positive Work Environment May Prolong Life
People who have a good peer support system at work may live longer than people who don’t, and this effect of peer social support on the risk of mortality was most pronounced among those between the ages of 38 and 43 years. Arie Shirom, from Tel Aviv University, and colleagues reviewed the medical records of 820 adults who were followed for 20 years, from 1988 to 2008. The workers came from some of Israel’s largest firms in finance, insurance, public utilities, healthcare and manufacturing, reported working on average 8.8 hours a day, who had been referred to a screening centre in Israel for routine examinations. The researchers controlled for confounding health factors, and obtained data on the control variables from each person’s periodic health examinations, including tests of physiological risk factors and a questionnaire completed during the examinations by all participants.  In addition, participants were administered another questionnaire that measured job demands, control at work and peer and supervisor support. The researchers rated peer social support as being high if participants reported that their co-workers were helpful in solving problems and that they were friendly. Control and decision authority were rated high if participants said they were able to use their initiative and had opportunities to decide how best to use their skills, and were free to make decisions on how to accomplish the tasks assigned to them and what to do in their jobs. The team reported that “the risk of mortality was significantly lower for those reporting high levels of peer social support,” explaining that: “Peer social support is a protective factor, reducing the risk of mortality.”

Dr Klatz observes: An Israeli team reports that people who have a good peer support system at work may live longer than people who don’t maintain a peer support network, reaffirming the anti-aging benefits of positive social relationships.

Fitness Test Could Predict Stroke Risk
A person’s physical fitness levels measured by treadmill performance in middle-age may predict the risk of dying of heart attack or stroke decades later for men and could be an early indicator of cardiovascular disease for women. Jarett D. Berry, from University of Texas Southwestern Medical Center, and colleagues examined more than 66,000 participants without cardiovascular disease, ages 20 to 90 years. They were then followed until death or the end of the study period; follow-up lasted up to 36 years. There were 1,621 cardiovascular deaths during the study. The team reports that: “A single measurement of fitness significantly improves classification of both short-term (10-year) and long-term (25-year) risk for [cardiovascular disease] mortality when added to traditional risk factors.”

Remarks Dr Goldman: Finding that how fast a person runs a mile on a treadmill may correlate to lifetime risk of cardiovascular incidents, these researchers reveal a simple, effective, and reliable assessment method for a leading and avertable cause of death.

Citrus Extracts Aid Metabolism
Previous studies of bitter orange (Citrus aurantium), containing the alkaloid p-synephrine, have suggested potential utility for weight management. Sidney J. Stohs, from Creighton University in Nebraska, and colleagues tested the potential of p-synephrine alone, or p-synephrine plus the citrus flavonoids naringin and hesperidin, on the metabolic rate of 50 study subjects. Results showed that the p-synephrine alone increased the metabolic rate by 7 percent, compared to a placebo. When 50mg of p-synephrine was consumed with 600 mg naringin and 100 mg hesperidin, the metabolic rate was almost 18 percent higher than the control group. No adverse effects to heart rate or blood pressure were observed. The researchers propose that: “This unusual finding of a thermogenic combination of ingredients that elevated metabolic rates without corresponding elevations in blood pressure and heart-rates warrants longer term studies to assess its value as a weight control agent.”

Comments Dr Klatz: Revealing that bitter orange extracts plus the citrus flavonoids, naringin and hesperidin, may boost metabolic rates without affecting blood pressure, this team suggests a important natural food that may potentially serve as an effective weight management agent.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription to Longevity Magazine™ e-Journal.

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