November 11-17, 2011

By Dr Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, and Dr Ronald Klatz, M.D., D.O., A4M President, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.

Dietary Habits May Help to Prevent Alzheimer’s  
The most common form of dementia among the aging population, Alzheimer’s Disease may be beneficially impacted by dietary habits. Fiorella Biasi, from University of Turin, and colleagues authored a review of studies regarding the influence of dietary habits on the onset and progression of Alzheimer’s Disease. The team reports that changes in the metabolism of lipids, with the accumulation of oxidized derivatives, may contribute to the onset and progression of Alzheimer’s. Specifically, the researchers take note of a critical balance between omega-3 and omega-6 fatty acids, and cholesterol, as a key contributor to the onset of Alzheimer’s, because these nutrients are essential for brain homeostasis. As well, the team notes that several studies indicate the consumption of flavonoids, a type of antioxidant vitamin, corresponds to a lower incidence of Alzheimer’s. The authors conclude that:  “The use of a diet with an appropriate [omega-3 to omega-6 fatty acids] ratio, rich in healthy oils, fish and antioxidants, such as flavonoids, but low in cholesterol-containing foods, can be a beneficial component in the clinical strategies of prevention of [Alzheimer’s Disease].”

Dr Klatz observes: Concluding that a diet rich in omega-3 and omega-6 fatty acids, as well as antioxidant vitamins, may beneficially impact the onset of Alzheimer’s Disease, these researchers submit key evidence supporting the notion that dietary interventions that may help to delay dementia.

Exercise & Healthy Fats Boosts Bone Health      
Studies have suggested that dietary fats and physical activity influence bone health. B. Tartibian, from Urmia University in Iran, and colleagues enrolled 79 healthy post-menopausal women, assigning them to one of four groups: group 1 was the control (no supplements or exercise); group 2 engaged in aerobic exercise (walking and jogging, achieving up to 65 percent of maximum heart rate); group 3 received a daily supplement of 1000 mg omega-3 (as 180 mg EPA/120 mg DHA); and group 4 received both the supplement and engaged in aerobic activity. After 24 weeks, the team found that the combined omega-3/exercise group displayed bone mineral density (BMD) increases of 15 percent in the lower back, and 19 percent in the thigh bone at the hip. As well, inflammatory markers among the combined omega-3/exercise group improved: levels of interleukin-6 (IL-6) were reduced by 40 percent, and tumour necrosis factor (TNF) decreased by 80 percent. The study authors submit that: “The present study demonstrates that long-term aerobic exercise training plus [omega-3] supplementation have a synergistic effect in attenuating inflammation and augmenting [bone mineral density] in post-menopausal osteoporosis.”

Remarks Dr Goldman: Finding that postmenopausal women who engage in aerobic exercise and consume of omega-3 fatty acids have improved bone mineral density (BMD), this team submits an effective approach to bone health that is accessible and easy to implement.

Ginger May Reduce Colon Cancer Risks      
Previously, a number of studies have demonstrated ginger’s potential as an anti-inflammatory agent. Suzanna M. Zick, from the University of Michigan Medical Center, completed a study involving 30 men and women, who consumed either a supplement containing 2 g of ginger extract (equivalent to 20 g of raw ginger root), or a placebo, daily for 28 days. The researchers found that certain markers of inflammation, known as eicosonoids, were reduced by 28 percent among the subjects who consumed the ginger supplement. The team reports that: “Ginger has the potential to decrease eicosanoid levels … [and] also seemed to be tolerable and safe.”

Comments Dr Klatz: By reducing inflammation, ginger may help to reduce the risk of developing colorectal cancer. This is an important discovery that furthers the evidence suggesting a functional health role for this food.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavours and to sign-up for your free subscription to Longevity Magazine™ e-Journal.

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