August 17-30, 2012

By Dr Robert Goldman & Dr Ronald Klatz

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent and treat aging related disease and to promote research into methods to retard and optimise the human aging process. Dr Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, and Dr Ronald Klatz, M.D., D.O., A4M President, physician co-founders of the anti-aging medical movement, distil these headlines and provide their commentary.

Cinnamon Improves Diabetes Markers
Whereas almost 24 million Americans live with diabetes, the number of people affected by the disease is predicted to vastly increase, as a result of the aging population. Previous research has suggested that active compounds in cinnamon may improve markers associated with diabetes. Yan Chen, from Chinese Academy of Sciences (China), and colleagues enrolled 66 type-2 diabetics, to receive a water extract of cinnamon at 120 mg a day, 360 mg a day, are placebo, for a three month period. The team found that fasting blood glucose levels was reduced by an average of 1.01 mmol/L in the subjects receiving 120 mg of cinnamon extract, and by 1.62 mmol/L in the group receiving 360 mg; no change was observed in the placebo group. As well, blood triglyceride levels decreased by 0.78 mmol/L in the subjects receiving 120 mg of cinnamon extract. The study authors conclude that: “our study indicates that cinnamon supplementation is able to significantly improve blood glucose control in Chinese patients with type 2 diabetes.”

Dr Klatz observes: Reporting that blood sugar control, and triglyceride levels, among type-2 diabetics improve with cinnamon supplementation, these researchers add to previous evidence suggesting a potential non-drug approach to diabetes management.

B Vitamins Linked to Cognitive Function
Previously, a number of studies have reported that high levels of homocysteine relate to an increased risk of cognitive decline, and that B vitamins may serve as cofactors for enzymes involved in the metabolism of homocysteine. Aron M. Troen, from Tufts University (Massachusetts, US), and colleagues analyzed data from 2000 study subjects who participated in The Boston Puerto Rican Health Study and the Nutrition, Aging, and Memory in Elders study. The researchers found that low levels of vitamin B-6 and B-12 are associated with an increased risk of impaired cognition. Further, the team found that low levels of B-12 were associated with an increased risk of depression.

Remarks Dr Goldman: Finding that low levels of vitamin B-6 and B-12 associate with an increased risk of impaired cognition, this team reveals further data suggesting the importance of vitamin nutrients in maintaining brain function as we age.

Blueberries May Lower Cholesterol
High in anthocyanins and flavonols, potent antioxidant compounds, blueberries have been associated with a number of positive health effects. Researchers from The Chinese University of Hong Kong supplemented diets with 0.5% and 1% blueberry anthocyanins, for six weeks, in an animal model. The team observed a resulting 37% and 66% increase, respectively, in bile acid excretion. As well, sterol excretion increased by 29 and 74%, respectively in both groups. The study authors conclude that: “The cholesterol-lowering activity of blueberry anthocyanins was most likely mediated by enhancing the excretion of sterols accompanied with down-regulation on gene expression of [major receptors, enzymes, and transporters involved in cholesterol metabolism.]”

Comments Dr Klatz: By promoting the biological processes necessary for achieving healthy cholesterol levels, blueberries demonstrate the potential to serve a functional health role in managing cholesterol.

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavours and to sign-up for your free subscription to Longevity Magazine™ e-Journal.

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