May 24-30, 2013

By Dr. Ronald Klatz & Dr. Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Exercise Your Brain
Raza Naqvi, from University of Toronto (Canada), and colleagues reviewed 32 randomized controlled trials to assess assorted therapies purported to address age-related cognitive decline.  The researchers found that mental exercise showed benefits in the three clinical trials included in the review. This involved computerized training programs or intensive one-on-one personal cognitive training in memory, reasoning or speed of processing. In one trial, participants had significantly improved memory during 5-year follow-up periods. Another study showed an improvement in auditory memory and attention in a group of seniors who participated in a computerized cognitive training program.   Citing that: ” The studies in this review that assessed cognitive exercises used exercises that were both labor- and resource-intensive,” the lead author suggests that: “we encourage researchers to consider easily accessible tools such as crossword puzzles and Sudoku.”

Dr. Klatz observes: “Mild cognitive impairment (cognitive decline that is more than normal for someone of a specific age) affects 10%-25% of people over age 70. The annual rate of decline to dementia (which is cognitive decline in several areas along with some functional ability) is about 10%. These researchers report that cognitive training exercises – and completing crossword puzzles and Sudoku – may help to prevent cognitive decline in aging.”

Combat Aches & Pains with Exercise
Lars L. Andersen, from the National Research Center for the Working Environment (The Netherlands), and colleagues recruited 20 women to do a shoulder exercise while on a resistance machine.  The women shrugged their shoulders while the machine applied resistance, which engaged the trapezius muscle between the neck and shoulders.  Two days later, the women came back to the lab with aching trapezius muscles, and they received a 10-minute massage on one shoulder and did a 10-minute exercise on the other shoulder. The exercise again involved shoulder shrugs; this time the women gripped an elastic tube held down by their foot to give some resistance. The team found that, as compared to the shoulder that wasn’t getting any attention, massage and exercise each helped diminish muscle soreness.  The effect peaked 10 minutes after each treatment, with women reporting a reduction in their pain of 0.8 points after the warm up exercise and 0.7 points after the massage. The study authors write that: “Coaches, therapists and athletes can use either active warm-up or massage to reduce [delayed onset muscle soreness]  acutely, e.g. before competition or strenuous work, but should be aware that the effect is temporary, i.e. the greatest effects occurs during the first 20 min after treatment and diminishes within an hour.”

Remarks Dr. Goldman: “While massage is commonly believed to be the best modality for relieving muscle soreness, emerging evidence suggests that actively warming up the muscles with exercise may be an effective alternative. Data from this team suggests that post-workout aches and pains can be effectively relieved by a short bout of light exercise.”

Barley Compounds May Help Weight Management Goals
Elin V Johansson, from Lund University (Sweden), and colleagues evaluated the potential effects of a whole grain barley kernel product, rich in intrinsic indigestible carbohydrates (dietary fiber and resistant starch), on markers of metabolism and appetite regulation in healthy men and women. The team enrolled 19 young adults, each of whom was randomly assigned to consume late evening meals with additional boiled barley kernels, or white wheat bread.  Blood samples were collected during the following breakfast and lunch times.  The barley kernels associated with an increase in glucagon-like-peptide-1 (GLP-1), a satiety hormone, as compared to white bread. Further, the group consuming the barley kernels experienced a decrease in free fatty acid levels and reduced inflammatory markers.  The team also observed a significant reduction in energy intake during lunch the next day among the barley consumers, as compared to the white bread group.   The study authors conclude that: “The results indicate that the [barley kernel]  evening meal, facilitate glucose regulation, increase the release of GLP-1, reduce subsequent energy intake while at the same time decreasing hunger over 2 subsequent meals, and fasting ;free fatty acids] the subsequent morning, possibly mediated through gut microbial fermentation of the indigestible carbohydrates.”

Comments Dr. Klatz: “Expanding on previous animal models suggesting that gut microbial metabolism may affect host metabolism, including appetite regulating hormones, these researchers report that the indigestible carbohydrate content in barley kernels may increase satiety hormones and reduce subsequent energy intake.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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