June 14-20, 2013

By Dr. Ronald Klatz & Dr. Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Western-Style Diet Linked to Premature Death
Tasnime Akbaraly, from INSERM (France), and colleagues examined whether diet, assessed in midlife, predicts future aging and disease.  The team used the Alternative Healthy Eating Index (AHEI), an index of diet quality, originally designed to provide dietary guidelines with the specific intention to combat major chronic conditions such as cardiovascular diseases and diabetes.  The researchers assessed data drawn from the British Whitehall II cohort study involving  5,350 adults (average age 51.3 years).  They found that following the AHEI can double the odds of reversing metabolic syndrome, a condition known to be a strong predictor of heart disease and mortality. Conversely, the team determined that participants with low adherence to the AHEI increased their risk of cardiovascular and noncardiovascular death. Those who followed a “Western-type diet” consisting of fried and sweet food, processed food and red meat, refined grains, and high-fat dairy products lowered their chances for ideal aging.  The study authors conclude that: “By considering healthy aging as a composite of cardiovascular, metabolic, musculoskeletal, respiratory, mental, and cognitive function, the present study offers a new perspective on the impact of diet on aging phenotypes.”

Dr. Klatz observes: “Numerous previous studies suggest a role for diet on specific aging-related diseases – most notably, heart disease and diabetes.  These researchers add to the data supporting this relationship, finding that diets laden with fried and sweet foods, processed and red meats refined grains, and high-fat dairy products reduce a person’s likelihood of achieving older ages in good health and with higher functionality.”

Combined Exercise & Diet Is Best Approach for Longevity
Abby C. King, from Stanford University School of Medicine (Californioa, USA), and colleagues split 200 initially inactive participants, ages 45 and older and with suboptimal diets, into four different groups. Each group received a different kind of telephone coaching. The first group learned to make changes to diet and exercise at the same time. The second group learned to make dietary changes first and didn’t try changing their exercise habits until a few months later. The third group reversed that order and learned to change exercise habits before adding healthy dietary advice. The fourth group, for comparison, did not make any dietary or exercise changes, but was taught stress-management techniques. Researchers tracked participants’ progress in all four groups for a year.  Despite the challenge of making multiple changes to their already-busy routines at once, those who began changing diet and exercise habits at the same time were most likely to meet national guidelines for exercise – 150 minutes per week – and nutrition – five to nine servings of fruit and vegetables daily, and keeping calories from saturated fats at 10 percent or less of their total intake.  Those who started with exercise first did a good job of meeting both the exercise and diet goals, though not quite as good as those who focused on diet and exercise simultaneously. The participants who started with diet first did a good job meeting the dietary goals but didn’t meet their exercise goals, suggesting” a possible behavioral suppression effect of early dietary intervention on [physical activity] that merits investigation.”

Remarks Dr. Goldman: “To achieve and maintain health, most of us consider exercise “or” eating right.  Stanford University School of Medicine researchers submit that changing exercise and diet at the same time gives a bigger boost than tackling them sequentially. They also found that focusing on changing diet first – an approach that many weight-loss programs advocate – may actually interfere with establishing a consistent exercise routine.”

Mango Modules Blood Sugar
Edralin Lucas, from Oklahoma State University (Oklahoma, USA), and colleagues examined the effects of daily mango consumption on clinical parameters and body composition in obese subjects (body mass index [BMI] at/above 30kg/m2). Twenty adults (11 males and 9 females) participated in the study, which included daily dietary supplementation with 10 grams of freeze dried mango (equivalent to approximately 100 grams of fresh mango, for 12 weeks.  The researchers observed that blood sugar levels at the conclusion of the study were significantly lower than the baseline in all subjects; BMI increased significantly in female subjects but not male subjects.   Writing that: “These results suggests that addition of mango to the diet may provide an alternative approach to modulating blood glucose without negatively affecting skeletal health” the study authors submit that: “the bioactive component(s) in mango and the mechanisms by which it modulates blood glucose and exerts potentially osteoprotective benefits warrants further investigation.”

Comments Dr. Klatz: “A fleshy stone fruit belonging to the genus Mangifera, consisting of numerous tropical fruiting trees in the flowering plant family Anacardiaceae, the mango is rich in vitamins, minerals and anti-oxidants, and contains an enzyme that can act as a digestive aid.  This data suggests that mango fruit helps to improve blood glucose levels; as well, it may improve BMI among women.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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