July 19-25, 2013
By Dr. Ronald Klatz & Dr. Robert Goldman
Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.
Short Walks Protect Against Diabetes
High post-meal blood sugar is a strong determinant of excessive 24-hour glucose levels, and research suggests that people who eat a big afternoon or evening meal and often then are sedentary for the remainder of the day, are at-risk for rapid blood sugar spikes that can potentially cause damage. Loretta DiPietro, from George Washington University School of Public Health & Health Services (Washington DC, USA), and colleagues enrolled ten men and women, ages 60 years and older, who were otherwise healthy but at risk of developing type 2 diabetes due to higher-than-normal levels of fasting blood sugar and to insufficient levels of physical activity. Subjects completed three randomly-ordered exercise protocols spaced four weeks apart. Each protocol comprised a 48-hour stay in a whole-room calorimeter, with the first day serving as a control period. On the second day, participants engaged in either post-meal walking for 15 minutes after each meal or 45 minutes of sustained walking performed at 10:30 in the morning or at 4:30 in the afternoon. All walking was performed on a treadmill at an easy-to-moderate pace. Participants ate standardized meals and their blood sugar levels were measured continuously over each 48 hour stay. The researchers observed that the most effective time to go for a post-meal walk was after the evening meal. The exaggerated rise in blood sugar after this meal – often the largest of the day – often lasts well into the night and early morning and this was curbed significantly as soon as the participants started to walk on the treadmill. The study authors write that: “Short, intermittent bouts of postmeal walking appear to be an effective way to control postprandial hyperglycemia in older people.”
Dr. Klatz observes: “Pre-diabetes is a condition that shows no or negligible signs and can be responsive to preventive strategies that may help to prevent progression to type-2 diabetes. This data suggests that fifteen-minute walks taken after meals help to curb blood sugar spikes.”
Food for Thought
Nikolaos Scarmeas, from Columbia University Medical Center (New York, USA), and colleagues studied 522 men and women, ages 55 to 80 years, who were absent of cardiovascular disease but at high vascular risk due to underlying diseases or conditions – such as type-2 diabetes, high blood pressure, high blood fats, overweight, and other factors. Study subjects consumed a Mediterranean diet for an average of 6.5 years, either supplemented with added extra-virgin olive oil or mixed nuts; or a low-fat regimen. At the end of the study period. the subjects were tested for signs of cognitive decline via standardized assessments. The researchers found that 60 subjects developed mild cognitive impairment: 18 on the olive oil supplemented Mediterranean diet; 19 on the diet with added mixed nuts; 23 in the control group. A further 35 subjects developed dementia: 12 on the added olive oil diet; six on the diet with added mixed nuts; 17 in the control group. The average scores on standardized cognitive testing for significantly higher for those subjects following either of Mediterranean diet variations, as compared to those in the control group. The team suggests that this study is the first long-term trial to assess the type of Mediterranean diet on brain power, and that it adds to the increasing body of evidence suggesting that a high-quality dietary pattern seems to protect cognitive function in the aging brain.
Remarks Dr. Goldman: “Previously, a number of studies have shown that adherence to a Mediterranean diet – rich in olive oil, nuts, as well as fruits, vegetables, and legumes, and limited amounts of dairy products, red meat, soda drinks, processed meats, and sweets – inversely associates with cardiovascular risks. These researchers report that consuming a Mediterranean diet improves the brain power of older men and women at high vascular risk due to underlying diseases or conditions.”
Calcium Cuts Death Risk
Lisa Langsetmo, from McGill University (Canada) , and colleagues examined data collected on 9,033 subjects enrolled in the Canadian Multicentre Osteoporosis Study (CaMOS) which had a 10-year follow-up during which 1,160 deaths occurred. The researchers found that daily calcium supplements up to 1000 mg reduced mortality among the women, and the results were inconclusive for supplemental intake exceeding that amount. Consequently, the study authors submit that: “Calcium supplements, up to 1000 mg/d, and increased dietary intake of calcium may be associated with reduced risk of mortality in women.”
Comments Dr. Klatz: “Previously, a number of studies have suggested that calcium helps to improve lipid profiles and reduce elevated blood pressure. These researchers reveal that daily supplements of calcium up to 1000 mg may reduce mortality, among women.”
Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
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