Aug. 30-Sept. 5, 2013

By Dr. Ronald Klatz & Dr. Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Multivitamin May Improve Mood & Wellbeing
David Camfield, from Swinburne University (Australia), and colleagues studied 138 healthy adults, ages 20 to 50 years, to whom a multivitamin was administered for 16 weeks.  Via at-home mobile-phone assessments, subjects reported “significantly reduced stress, physical fatigue and anxiety” after taking the multivitamin.

Dr. Klatz observes: “The most commonly used supplement in the developed world, multivitamins are formulated with a composition that mimics a diverse assortment of healthy fruit and vegetable compounds. Australian researchers report that a daily multivitamin supplement exerts beneficial effects on stress, anxiety and fatigue.”

Boost Physical Activity to Shed Fat
Previously, researchers from Pittsburgh Children’s Hospital (Pennsylvania, USA) report that increasing physical activity – without caloric restriction – is effective in reducing total, fat, visceral obesity, and liver fat in obese adolescent boys.  SoJung Lee and colleagues engaged in a similar study to ascertain insights for teenage girls.  The researchers enrolled 40 obese adolescent girls with BMIs in the 95th percentile or greater for their age. They were randomized to 3 months of aerobic exercise, with three 60-minute sessions on a treadmill a week; resistance exercise consisting of working out on a weigh machine three times a week, for 60 minutes a session; or a sedentary control group.  The teens were allowed to continue to eat as before.  Compared with controls, body weight dropped 1.3 kg in the aerobic exercise group and 0.3 kg in the resistance training group.  Despite the absence of weight loss, total fat decreased 1.5% in the aerobic exercise group and 1.4% in the resistance training group compared with controls.  Visceral fat dropped 19% and lipid fat decreased 43% in the aerobic arm compared with the control arm. Also, insulin sensitivity improved 23% in the girls who did aerobics compared with the sedentary teens.

Remarks Dr. Goldman: “Overweight – obesity has reached critical levels among youths, especially teens.  This team reports that both aerobic exercise and resistance training are effective at reducing body fat, among previously sedentary adolescent girls.”

B Vitamin Confers DNA Protection    
Keisuke Kuwahara, from the National Center for Global Health and Medicine (Japan), and colleagues studied 500 subjects (293 men and 207 women), ages 21 to 66 years, employed at two municipal offices in Japan. Observing that pyridoxal – one of three forms of vitamin B6 – associated with lower urinary 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative DNA damage, in men, the study authors write that: “The results suggest that vitamin B6 plays a role against oxidative DNA damage.”

Comments Dr. Klatz: “Previous studies link a higher vitamin B status with a lower risk for cancer. Japanese researchers have now elucidated the exact mechanism by which this may occur, finding that higher blood levels of Vitamin B6 associate with less damage to DNA, among men.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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