Nov. 29-Dec. 5, 2013

By Dr. Ronald Klatz and Dr. Robert Goldman

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Omega-3 s May Reduce Biological Age
Telomeres are the end caps of chromosomes, protecting the DNA complexes from deterioration during cell division. Telomere shortening is considered a marker of cellular aging, and prematurely shortened telomeres have been linked to increased risk of cancers, heart disease, dementia and death.  Nathan O’Callaghan, from the Commonwealth Scientific and Industrial Research Organisation (CSIRO; Australia), and colleagues enrolled 33 men and women, ages 65 years and older, with mild cognitive impairment, assigning each to one of 3 groups: the first group received EPA (eicopentaenoic acid)  omega-3 supplements (1.67 grams EPA & 16 g, the second group received docosahexaenoic acid (DHA) omega-3 supplements  (1.55 g DHA & 0.40 g EPA/day), and the third group received omega-6 linoleic acid (2.2 g/day) for six months.  The team observed that DHA reduced the shortening of telomeres, while omega-6 exerted the greatest shortening of telomere length.  The study authors conclude that: “Telomeric shortening may be attenuated by [omega-3 polyunsaturated fatty acid] supplementation.”

Dr. Klatz observes: “Australian team reports that supplementation of omega-3 fatty acids may reduce telomere shortening to thus slow cellular aging, among older men and women  with mild cognitive impairment.”

Resistance Training Protects Against Heart Disease
Christian K. Roberts, from the University of California/Los Angeles (UCLA; California, USA), and colleagues assessed the molecular behavior of high-density lipoprotein (HDL; “good” cholesterol), in young men who weight trained regularly, as compared to sedentary counterparts.  The researchers found that the men who didn’t exercise were more likely than those who weight trained to have dysfunctional HDL. Having faulty HDL was associated with numerous other risk factors for heart disease, including high triglycerides and a higher trunk fat mass. This finding held true regardless of the men’s weight, which suggests that maintaining a “healthy” weight isn’t as important for healthy cholesterol function as being active by regularly performing strength training.  Observing that: “Chronic [resistance training] is associated with improved HDL redox activity,” the study authors submit that: “This may contribute to the beneficial effects of [resistance training] on reducing cardiovascular disease risk, irrespective of body weight status.”

Remarks Dr. Goldman: “Exercise has the potential to protect against heart disease in a variety of ways. Now researchers find that weight training helps to promote proper functioning of high-density lipoprotein (HDL; “good” cholesterol), among young men.”

Adequate Sleep Is An Anti-Aging Essential
Jae-Hyun Kim, from Yonsei  University (South Korea), and colleagues examined the relationship between sleep duration and self-rated health in Korean adults  The team used data collected on 15,252 participants in the Korea National Health and Nutrition Examination Survey IV. Results showed that short sleep duration of 5 hours or less per day and long sleep duration of 9 hours or more per day associated with poor self-rated health.

Comments Dr. Klatz: “Study authors find that sleeping less than 5 hours a day, as well as 9 or more hours a day, associates with poor physical and mental health.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.
Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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