June 6-12. 2014

By Dr. Robert Goldman & Dr. Ronald Klatz

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Confidence Counters Stress
A team from Concordia University (Canada) suggests that it is as important for older adults to maintain and improve upon those confidence levels as they enter their twilight years.   Sarah Y. Liu and colleagues met with 147 adults, ages 60 years and over, to measure their cortisol levels, self-esteem, stress, and symptoms of depression every 24 months over four years. Self-esteem was measured through standardized questions.  The study also took into account personal and health factors like economic status, whether the participant was married or single, and mortality risk.  The team revealed that maintaining or even improving self-esteem may help to buffer potential health threats typically associated with the transition into older adulthood.

Dr. Klatz observes: “Whereas a number of previous studies demonstrate the importance of boosting self-esteem in one’s adolescent years, Canadian researchers report that people who have a confident self-esteem tend to experience fewer health problems as they age.”

Exercise Stimulates Stem Cells
University of Utah (Utah, USA) researchers report that moderate exercise helps to regenerate muscle mass, in a lab animal model.  Typically, regeneration, maintenance and repair of adult skeletal muscle damage due to aging and/or chronic stress states require activation of satellite cells (stem cells). Rajasekaran Namakkal Soorappan and colleagues found that aged mice lacking Nrf2 that underwent two weeks of endurance exercise stress on treadmills showed poor stem cell regeneration, which is likely to hinder the recovery of lost muscle mass. Nrf2 is protein that regulates the production of antioxidants in the body.  In the group that couldn’t produce Nrf2, endurance exercise stress on the treadmills affected stem cell protein expression and limited skeletal muscle regenerative capacity. Commenting that: “Physical activity is the key to everything,” the lead investigator submits that: “we believe that moderate exercise could be one of the key ways to induce stem cells to regenerate especially during senescence.”

Remarks Dr. Goldman: “Vast evidence demonstrates the beneficial effects of physical activity on weight, heart health, and other key aspects of health and wellness.   This US team reports that moderate exercise helps to regenerate muscle mass, in a lab animal model.”

Almonds Aid Digestive Health
Zhibin Liu, from Fuzhou University (China), and colleagues enrolled 48 healthy men and women, ages 18 to 22 years, in a study in which the participants either: received 56 grams of roasted almonds added daily to their diet; added 10 grams of almond skins daily to their diet; or consumed 8 grams per day of fructooligosaccharides (control group).  After six weeks, the data revealed that the almonds and almond skins significantly increased Bifidobacterium spp. and Lactobacillus spp. populations. Among the almond skin group, the enhanced levels of “good bacteria” were sustained for two weeks after the intervention period concluded.  Among the roasted almonds group, the beneficial changes were not seen until week six.  The study authors conclude that: “Our observations suggest that almond and almond skin ingestion may lead to an improvement in the intestinal microbiota profile and a modification of the intestinal bacterial activities, which would induce the promotion of health beneficial factors and the inhibition of harmful factors. Thus we believe that almonds and almond skins possess potential prebiotic properties.”

Comments Dr. Klatz: “Prebiotics are compounds that help to promote “good bacteria” (probiotics) in the gastrointestinal tract, with which a wide variety of beneficial health effects are associated.  Rich in fiber and plant phytochemicals, almonds may help boost levels of ‘good bacteria’ in the gut.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.  Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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