June 13 – 19, 2014

By Dr. Robert Goldman & Dr. Ronald Klatz

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Be Brainy

Nicole Schneeweis, from Linz University (Austria), and colleagues examined variation in years of schooling arising from compulsory educational reforms implemented in six European countries during the 1950s and 1960s, measuring mental functioning in seniors with various levels of schooling.  The data was yielded from individuals aged around 60 years, enrolled in the Survey of Health, Aging and Retirement in Europe.  The team observed that the burden of demographic change is likely to depend more on how healthy and mentally fit people are at different ages than on the exact age structure of people in a population. The study also shows that education tends to significantly boost brain function, and that this effect persists as a person ages.  The study shows that people who attended school for longer periods because of new regulations performed better in terms of cognitive functioning than those who did not. The researchers found a positive impact of schooling on memory scores. Importantly, the study finds evidence for a protective effect of schooling for the brain: more education slows cognitive decline. The study authors submit that education can be an important measure for maintaining cognitive functioning and protecting against cognitive decline, observing that: “One year of education increases the memory score approximately four decades later by about 0.2, which amounts to 10 % of a standard deviation.”

Dr. Klatz observes: “In that the populations of developed countries are growing older, some experts are concerned that average cognition levels and national productivity may begin to decline, and the incidence of dementia may rise.  Austrian team finds that long after compulsory schooling ends, education continues to enhance cognitive functions.”

Bigger Muscles Linked to Lower Risk of Dying

Preethi Srikanthan, an assistant clinical professor in the endocrinology division at the David Geffen School of Medicine at UCLA, and colleagues analyzed body composition data obtained from 3,659 men (aged 55 and over) and women (aged 65 and over) who took part in the National Health and Nutrition Examination Survey (NHANES) III, between 1988 and 1994. The authors then determined how many of the participants had died from natural causes based on a follow-up survey carried out in 2004. Results showed that all-cause mortality was significantly lower in participants with the highest muscle mass index than it was in participants with the lowest muscle mass. “In other words, the greater your muscle mass, the lower your risk of death,” said study co-author Dr. Arun Karlamangla, an associate professor in the geriatrics division at UCLA. “Thus, rather than worrying about weight or body mass index, we should be trying to maximize and maintain muscle mass.”

Remarks Dr. Goldman: “US researchers report data to suggest that the more muscle mass an older person has, the less likely they are to die prematurely.”

Peach Compounds Inhibit Breast Cancer Growth

Dr. Luis Cisneros-Zevallos, a food scientist at Texas A&M AgriLife Research, and colleagues at both Texas A&M and Washington State University, implanted aggressive breast cancer cells under the skin of mice. After giving the cells a week to establish, the researchers began feeding the mice varying doses of peach polyphenols. Results showed that the mice fed with high-levels of polyphenols had tumors that grew less and without much of the blood vessel formation that helps cancer cells spread to other parts of the body. Furthermore, the tumors of the mice fed high-levels of the polyphenols also had less evidence of enzymes involved in the spread and invasion of cancer. “After determining the dose necessary to see the effects in mice, it was calculated that for humans it would be equivalent to consuming two to three peaches per day,” said Dr Cisneros-Zevallos. Study co-author Giuliana Noratto, assistant professor of food science at Washington State University, said that the results emphasize the role of good nutrition in cancer prevention. “Having enough fruits and vegetables that can provide these compounds in our diet, we might have a similar preventive effect,” said Noratto. “We are great believers that you can cure yourself by having a good diet and a good supply of medicinal plants.”

Comments Dr. Klatz:  “New data suggests that compounds found in peaches have been shown to inhibit both the growth of breast cancer cells and their ability to spread (metastasize).”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.  Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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