July 25-31, 2014

By Dr. Robert Goldman & Dr. Ronald Klatz

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 24,000 physician and scientist members from 110 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Funny Moments Counter Memory Loss
Lee Berk, from Loma Linda University (California, USA), and colleagues showed a 20-minute humorous video to a group of healthy seniors, as well as a group of seniors with diabetes. These groups were compared with a group of seniors who didn’t see the video.  The two groups that watched the funny video showed significant decreases in cortisol levels and greater improvements on memory tests, compared to the group that didn’t see the video. The diabetes group showed the largest decrease in cortisol levels, while the healthy group had the greatest improvement on memory tests.  The study authors propose that: “[humor and laughter] may be another non-pharmacological lifestyle intervention to provide health, wellness & adjunctive therapeutic benefits.”

Dr. Klatz observes: “Previously, studies suggest that cortisol – the stress hormone, can damage memory and learning as we age.  This research team submits that  by reducing levels of cortisol, humor and laughter may help combat aging-related memory loss.”

Move More to Maintain Memory
A study by Michigan State University (Michigan, USA) researchers investigating young, healthy adults reveals that aerobic fitness affects long-term memory. Kimberly M. Fenn and colleagues tested 75 college students during a two-day period and found those who were less physically fit had a harder time retaining information.  Reporting that: “Findings revealed an association between aerobic fitness and memory function such that individuals with lower cardiorespiratory fitness exhibited poorer implicit memory performance and poorer long-term memory retention,” the study authors submit that: “These data indicate that cardiorespiratory fitness may be important for the optimal function of neural networks underlying these memory systems.”

Remarks Dr. Goldman: “Adding to the wealth of reasons to maintain physically fit, researchers report that people who are aerobically fit tend to have better long-term memory skills.”

Two Foods that Assist Cardiovascular Health
Catherine Bondonno, from the University of Western Australia (Australia), and colleagues enrolled 30 healthy female and male volunteers, and screened them through a medical history questionnaire, electrocardiography, BMI, height and weight, blood pressure, and fasting blood samples. Subjects were randomly assigned into one of four interventions—a) apple: high flavonoid low nitrate; b) spinach: low flavonoid high nitrate; c) apple + spinach: high flavonoid high nitrate; d) control: low flavonoid low nitrate. Measuring plasma nitric oxide (NO) status in plasma, urine and saliva, and assessing cognitive performance and mood via standardized scales, separately the apples and spinach increased markers of NO in the plasma; and the spinach alone, and the apple + spinach combination, significantly improved markers of NO in saliva and urine as well.  The study authors conclude that: “flavonoid-rich apples and nitrate-rich spinach augmented [nitric oxide] status acutely with no concomitant improvements or deterioration in cognitive function and mood.”

Comments Dr. Klatz:  “Nitric oxide is an important molecule for cardiovascular and cognitive health, as it exerts effects on blood flow and blood vessel function.  Abundant in nitrate, spinach – and apples – plentiful in flavonoids, raise nitric oxide in the body.”

Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.  Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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