Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan. These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M; www.worldhealth.net), a non-profit medical society composed of 26,000 physician and scientist members from 120 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.
Anti-Aging = Pro-Cognition
Korean researchers completed a study assessing 460 community-residing seniors, ages 60 and older. Participants were randomized into 5 groups: group A received standard care services; group B received bimonthly (once every 2 months) telephonic care management; group C received monthly telephonic care management and educational materials similar to those in group B; group D received bimonthly health worker-initiated visits and counseling; and group E received bimonthly health worker-initiated visits, counseling, and rewards for adherence to the program. Researchers measured outcome via a standardized mental scale. Group E showed superior cognitive function to group A, with participation in cognitive activities being the most important determining factor among several health behaviors. Those subjects who were physically active, did not smoke, engaged in social functions, were cognitive active, drank alcohol in moderation, and learned about body mass and a healthy diet had the best outcomes. The study authors report that: “Engaging in cognitive activities, in combination with positive health behaviors, may be most beneficial in preserving cognitive abilities in community-dwelling older adults.”
Dr. Klatz observes: “Identifying a five-element program that may protect memory and attention skills, Korean researchers affirm the tenets of the anti-aging lifestyle that assist in retention of cognitive functions with age.”
Regular Exercise Lowers Breast Cancer Risk
Obesity has been associated with increased risk for postmenopausal breast cancer, with a number of published studies assessing with body mass index (BMI) which does not distinguish between fat and lean mass. Tim Key, from the Cancer Epidemiology Unit at Oxford University (United Kingdom), and colleagues assessed data collected in the UKL Biobank study, involving 125,788 postmenopausal women followed for five years, during which time 1,122 cases of invasive breast cancers occurred. During the study, researchers tracked body fat percentage while subjects self-reported physical activity and other lifestyle activities. The data revealed that vigorous physical activity reduced breast cancer risk by one-fifth, as compared to sedentary counterparts. Also, women with the most body fat were 55% more likely to develop breast cancer, as compared to leaner subjects. The study authors conclude that: “Our results show that women with a high percentage of body fat have a high risk for breast cancer, and suggest that vigorous physical activity protects against breast cancer, beyond its role in decreasing body fat percentage.”
Remarks Dr. Goldman: “Data from this UK study suggests that vigorous physical activity may reduce breast cancer risk by one-fifth, among postmenopausal women.”
Dual Approach Confers Heart Benefits
Endothelial cells line the blood vessels, for which healthy blood flow is critical to maintaining cardiovascular health. Markos Klonizakis, from Sheffield Hallam University (United Kingdom), and colleagues studied a group of 20 healthy but sedentary men and women, average age 55 years. During an eight-week period, one group was encouraged to eat more vegetables, fruit, olive oil, tree nuts and fresh oily fish – and engage in a program of moderate exercise regime; the second group engaged in exercise only. While both groups showed improved microvascular responses, the group on the Mediterranean-style diet plus exercise demonstrated a stronger improvement. Importantly, these improvements were sustained one year later, whether or not the subjects still followed the study-related lifestyle guidelines. The study authors submit that: “a brief intervention combining [Mediterranean-style diet] with exercise in this group [at high risk of developing cardiovascular disease] promises long-term health benefits.””
Comments Dr. Klatz: “A combined approach of a Mediterranean-style diet, along with a regular program of moderate exercise, may improve the blood flow in cells that line blood vessels.”
Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties. The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion. Visit the A4M’s World Health Network website, at www.worldhealth.net, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.