March 13-19, 2015

March 13-19, 2015

By Dr. Robert Goldman & Dr. Ronald Klatz

Longevity News and Review provides readers with the latest information in breakthroughs pertaining to the extension of the healthy human lifespan.  These news summaries are compiled by the American Academy of Anti-Aging Medicine (A4M;, a non-profit medical society composed of 26,000 physician and scientist members from 120 nations, united in a mission to advance biomedical technologies to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process.   Dr. Ronald Klatz, M.D., D.O., A4M President, and Dr. Robert Goldman, M.D., Ph.D., D.O., FAASP, A4M Chairman, physician co-founders of the anti-aging medical movement, distill these headlines and provide their insightful commentary.

Attitude & Longevity
Andrew Steptoe, from the University College London (United Kingdom), and colleagues analyzed data collected on over 6,000 adults, ages 52 years and older.  In 2004 or 2005, researchers asked the participants how old they felt. More than two-thirds felt at least three years younger than their real age, while a quarter felt their real age and less than 5% felt more than a year older.  The team followed the subjects through March 2013, finding that about 14% of those who felt younger had died, compared to about 19% of those who felt their age and about a quarter of those who felt older.

Dr. Klatz observes: “This large-scale study confirms the notion that feeling younger than your chronological age reduces the chances of dying.”

Muscle-Building Compound Benefits Blood Pressure
Eduardo Tibiri, from the School of Physical Education and Sports Sciences of the Estacio de Sa University (Brazil), and colleagues enrolled 40 healthy male, moderately physically active subjects, average age 27.7 years, to consume creatine as a dietary supplement (20 g/day of commercially available micronized creatine monohydrate), for one week.   Researchers used imaging to assess microvascular reactivity, and conducted video microscopy to ascertain capillary density.  Mean blood pressure decreased from 92.1 mm Hg, to 89.8.  Significant decreases of total cholesterol and LDL cholesterol were also observed.  The study authors submit that: “Oral supplementation with creatine in healthy, moderately physically active young adults improves systemic endothelial-dependent microvascular reactivity and increases skin capillary density and recruitment.”

Remarks Dr. Goldman: “A naturally-occurring compound that supplies energy to cells throughout the body – primarily muscle, creatine may improve microvascular reactivity and capillary density.”

Coffee Combats Alzheimer’s Risk
Arfram Ikram, from Erasmus Medical Centre Rotterdam (The Netherlands), and colleagues investigated compounds in coffee, identifying caffeine and polyphenols as key candidates. Caffeine appears to help prevent the formation of amyloid plaques and neurofibrulary tangles in the brain – two hallmarks of Alzheimer’s Disease. In addition to this, both caffeine and polyphenols may reduce inflammation and decrease the deterioration of brain cells – especially in the hippocampus and cortex, areas of the brain involved in memory. The lead investigator comments that: “The majority of human epidemiological studies suggest that regular coffee consumption over a lifetime is associated with a reduced risk of developing Alzheimer’s Disease, with an optimum protective effect occurring with three to five cups of coffee per day.”

Comments Dr. Klatz: “In that a number of previous studies link regular, moderate coffee consumption with a possible reduced risk of developing Alzheimer’s Disease, Netherlands team reports data that suggests that drinking 3-5 cups of coffee per day may exert a preventative effect.”
Anti-aging medicine is the fastest-growing medical specialty throughout the world and is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders, and diseases.  It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans.  As such, anti-aging medicine is based on solid scientific principles of responsible medical care that are consistent with those applied in other preventive health specialties.  The goal of anti-aging medicine is not to merely prolong the total years of an individual’s life, but to ensure that those years are enjoyed in a productive and vital fashion.  Visit the A4M’s World Health Network website, at, to learn more about the A4M and its educational endeavors and to sign-up for your free subscription o Longevity Magazine™ e-Journal.

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